A First Look at ARFome: Dual-Coding Genes in Mammalian Genomes
نویسندگان
چکیده
منابع مشابه
A First Look at ARFome: Dual-Coding Genes in Mammalian Genomes
Coding of multiple proteins by overlapping reading frames is not a feature one would associate with eukaryotic genes. Indeed, codependency between codons of overlapping protein-coding regions imposes a unique set of evolutionary constraints, making it a costly arrangement. Yet in cases of tightly coexpressed interacting proteins, dual coding may be advantageous. Here we show that although dual ...
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ژورنال
عنوان ژورنال: PLoS Computational Biology
سال: 2007
ISSN: 1553-7358
DOI: 10.1371/journal.pcbi.0030091